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        純度:99% 包裝:25Kg桶裝


        CAS:    1076-38-6
        分子式:    C9H6O3
        分子量:   162.14
        中文名稱:   4-羥基香豆素
        英文名稱:    4-hydroxy-2h-1-benzopyran-2-on
                             Benzotertonic acid
                             4-hydroxy coumarin
        性狀描述:    微黃色針狀結晶。熔點206℃。易溶于乙醇、乙醚和熱水。與三氯化鐵作用呈棕色。
        用途:    醫藥,農藥的中間體。用于生產雙香豆素、新抗凝,華法林等抗凝血藥物。這類4-羥基香豆素衍生物是一類口服抗凝血藥物。雙香豆素因吸收不規則、不完全,已被華法林等所取代。雙香豆素作用維持時間最長(4-7d),華法林較長(3-5d),新抗凝較短(2-4d),香豆素乙酯最短(2-3d)。




        Product Identification
        【Product Name】4-Hydroxy-1-benzopyran-2-one
        【Synonyms】4-Coumarinol  4-羥基香豆素
        【Molecular Weight】162.15
        【RTECS Class】Other
        【Beilstein Reference】5-17-11-00495

        Physical and Chemical Properties
        【Appearance】odorless white to off-white powder
        【Solubility in water】Slightly soluble
        【Melting Point】211-214℃
        【Boiling Point】349℃
        【Partition Coefficient】1.17

        First Aid Measures
        【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
        【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
        【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
        【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

        Handling and Storage
        【Storage】Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
        【Handling】Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

        Hazards Identification
        【Ingestion】May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
        【Inhalation】May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
        【Skin】May cause skin irritation.
        【Eyes】May cause eye irritation.
        【EC Risk Phrase】R 22
        【EC Safety Phrase】S 22 36/37

        Exposure Controls/Personal Protection
        【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
        【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

        Fire Fighting Measures
        【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Extinguishing media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

        Accidental Release Measures
        【Small spills/leaks】Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

        Stability and Reactivity
        【Disposal Code】3
        【Incompatibilities】Oxidizing agents.
        【Stability】Stable at room temperature in closed containers under normal storage and handling conditions.
        【Decomposition】Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

        Transport Information
        【HS Code】2932 29 80


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