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        純度:99.0% 包裝:按用戶要求


        CAS:  1620-98-0
        分子式:  C15H22O2
        分子量:  234.34

        中文名稱:  3,5-二叔丁基-4-羥基苯甲醛

        英文名稱:  3,5-di-tert-butyl-4-hydroxy-benzaldehyd

        性質描述:  該品為淡黃色至淺棕色片狀結晶。熔點187-190℃。

        外觀          淺黃至琥珀色片狀結晶或粉水 
        熔點          ≥188 
        含量          ≥99.0% (GC)
        干燥失重 ≤0.5%

        用途:   主要用作醫藥中間體,如新型非甾體抗炎藥環氧化酶-2和5-脂氧合酶雙重抑制劑-Darbufelone等藥物合成,它們用于治療類風濕關節炎和骨關節炎。


        Product Identification
        【Product Name】3,5-Di-tert-butyl-4-hydroxybenzaldehyde 3,5-二叔丁基-4-羥基苯甲醛
        【Molecular Weight】234.33
        【RTECS Class】Drug; Mutagen
        【Beilstein Reference】4-08-00-00601

        Physical and Chemical Properties
        【Appearance】Very slightly beige powder.
        【Solubility in water】Insoluble
        【Melting Point】190
        【Boiling Point】332
        【Density】1.16 g/cm3
        【pKa/pKb】8.33 (pKa)
        【Partition Coefficient】4.8

        First Aid Measures
        【Ingestion】If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
        【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
        【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
        【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

        Handling and Storage
        【Storage】Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
        【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

        Hazards Identification
        【Ingestion】May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
        【Inhalation】May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
        【Skin】May cause skin irritation. The toxicological properties of this material have not been fully investigated.
        【Eyes】May cause eye irritation. The toxicological properties of this material have not been fully investigated.
        【EC Risk Phrase】R 36/37/38
        【EC Safety Phrase】S 26 36

        Exposure Controls/Personal Protection
        【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
        【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

        Fire Fighting Measures
        【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

        Accidental Release Measures
        【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.

        Stability and Reactivity
        【Incompatibilities】Oxidizing agents, acid chlorides, copper, copper alloys, acid anhydrides.
        【Stability】Stable under normal temperatures and pressures.
        【Decomposition】Carbon monoxide, carbon dioxide.


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